Molecular Cytogenetic Diagnosis and Somatic Genome Variations
نویسندگان
چکیده
منابع مشابه
Molecular Cytogenetic Diagnosis and Somatic Genome Variations
Human molecular cytogenetics integrates the knowledge on chromosome and genome organization at the molecular and cellular levels in health and disease. Molecular cytogenetic diagnosis is an integral part of current genomic medicine and is the standard of care in medical genetics and cytogenetics, reproductive medicine, pediatrics, neuropsychiatry and oncology. Regardless numerous advances in th...
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It is hard to imagine that all the cells of the human organism (about 10(14)) share identical genome. Moreover, the number of mitoses (about 10(16)) required for the organism's development and maturation during ontogeny suggests that at least a proportion of them could be abnormal leading, thereby, to large-scale genomic alterations in somatic cells. Experimental data do demonstrate such genomi...
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ژورنال
عنوان ژورنال: Current Genomics
سال: 2010
ISSN: 1389-2029
DOI: 10.2174/138920210793176010